Interleukin-12

A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.

Also Known As:

IL 12; Interleukin 12; IL12; Interleukin-12 p70; Cytotoxic Lymphocyte Maturation Factor; IL-12 p70; Interleukin 12 p70; Edodekin Alfa; IL-12; Natural Killer Cell Stimulatory Factor

Pharmalogical Action Categories:

Adjuvants, Immunologic
Angiogenesis Inhibitors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Interleukins: 25880
        Interleukin-12: 9330
- Peptides: 84029
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Interleukins: 25880
        Interleukin-12: 9330
Biological Factors: 2560
- Intercellular Signaling Peptides and Proteins: 30151
  - Cytokines: 168239
    - Interleukins: 25880
      - Interleukin-12: 9330

Christine Seitz Selected Research

Christine Seitz Research Topics

Disease

Drug/Important Bio-Agent (IBA)